ea0035p731 | Neuroendocrinology | ECE2014
Andujar-Plata Paula
, Fernandez-Rodriguez Eva
, Quinteiro Celsa
, Casanueva Felipe
, Bernabeu Ignacio
Introduction: Human recombinant growth hormone (hrGH) treatment in adult patients with GH deficiency (GHD) has an important interindividual variability and several factors can influence it. The aims of the study were: i)- to analyze the genotype of GHR regarding exon 3 deletion (d3-GHR) in a serie of adult patients with GHD; ii)- to assess the effect of d3-GHR on initial IGF1 levels; iii)- to evaluate if d3-GHR and/or initial IGF1 levels were associated with adverse effects an...